{"product_id":"apaisyl-gel-0-75-after-insect-stings-gel-30-gr-special-offer-buy-3-get-1-apaisyl-roll-on-gel-15ml-free","title":"Apaisyl Gel 0.75% After Insect Stings Gel 30 Gr Special Offer: Buy 3 Get 1 + Apaisyl - Roll-On Gel 15ml Free!","description":"\u003ch3 data-pm-slice=\"1 1 []\"\u003e\u003c\/h3\u003e\n\u003ch3 data-pm-slice=\"1 1 []\"\u003e⭐ SPECIAL OFFER\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eBuy 3 Tubes of Apaisyl Gel 30g and receive 1 FREE Apaisyl - After-Stings Roll-On Gel 15ml!\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e The special offer applies only when the \u003cstrong\u003eSpecial Offer\u003c\/strong\u003e package option is selected.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe individual Apaisyl\u003c\/strong\u003e\u003cstrong\u003e options are sold separately and do not include the free box.\u003c\/strong\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDescription:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #ff2a00;\"\u003e\u003cstrong\u003eFOR FULL DETAILED DESCRIPTION AND WARNINGS PLEASE SEE BELOW.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eApaisyl Insect Bite Gel: Itch Relief, Insect Bites - Suitable from 30 months onwards. This product is recommended for teenagers, adults, and children. For pregnant women and breastfeeding mothers, use only upon medical advice. This gel is a medication containing an antihistamine for local use. It is specially formulated to alleviate itchiness, particularly in cases of insect bites. Apaisyl Insect Bite Gel comes in a 30g tube.\u003c\/p\u003e\n\u003cp\u003eThe active ingredient of the Apaisyl Gel is Chlorhydrate d'isothipendyl (0.750g per 100g of gel). Other ingredients include edetic acid, sodium carboxymethylcellulose, sorbic acid, non-crystallizable 70% sorbitol, sodium hydroxide, and purified water.\u003c\/p\u003e\n\u003cp\u003eUse Apaisyl Gel with caution. Due to the risk of the active ingredient entering the bloodstream, the gel should not be applied on mucous membranes, on a large surface, under an occlusive dressing, on damaged skin, or on premature infants or infants. It contains sorbic acid, which can cause local skin reactions such as eczema. In case of persistent or worsening discomfort, medical advice may be required as the itching may have other origins.\u003c\/p\u003e\n\u003cp\u003eApaisyl Gel should not be used during pregnancy and breastfeeding without consulting a doctor or pharmacist. If you are allergic to any antihistamine medication, do not use Apaisyl Gel. This product is not intended for use on infected, irritated, and oozing wounds.\u003c\/p\u003e\n\u003cp\u003eApaisyl Insect Bite Gel is intended for adults and children over 30 months old. It is to be applied on the skin 2-3 times a day for 3-5 days. If symptoms persist after 5 days, seek medical advice.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIndications:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eInsect stings.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eComposition:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAqua, Alcohol Denat, ALoe Barbasensis Leaf Juice, Menthol, Menthyl Lactate, Bisabolol, Glycyrrhetinic Acid, Algae Extract, Carbomer, Lecithin, Propylene Glycol, DIsodium EDTA, Sodium Sufate, Magnesium Chloride, Aminomethyl Propanol, Magnsium Nitrate, Citric Acid, Ascorbic Acid, Phenoxyethanol, Chlorphenesin, Sodium Benzoate, Potassium Sorbate, Sodium Dehydroacetate, .\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDirections:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIt is to be applied on the skin 2-3 times a day for 3-5 days. If symptoms persist after 5 days, seek medical advice\u003c\/span\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDetails:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEAN\/UPC: \u003cspan\u003e3400931717881\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eContents: 30 Grams\u003c\/p\u003e\n\u003cp\u003ePresentation: Tube - Gel\u003c\/p\u003e\n\u003cp\u003eFULL PRODUCT DISCLOSURE:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eNAME OF THE MEDICATION\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eAPAISYLGEL 0.75%, gel for topical application\u003c\/p\u003e\n\u003col start=\"2\"\u003e\n\u003cli\u003eQUALITATIVE AND QUANTITATIVE COMPOSITION\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eIsothipendyl Hydrochloride .................................................................................................. 0.750 g\u003c\/p\u003e\n\u003cp\u003eFor 100 g of gel for topical application.\u003c\/p\u003e\n\u003cp\u003eNoteworthy excipient: Sorbic Acid (E200).\u003c\/p\u003e\n\u003cp\u003eFor the complete list of excipients, see section 6.1.\u003c\/p\u003e\n\u003col start=\"3\"\u003e\n\u003cli\u003ePHARMACEUTICAL FORM\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eGel for topical application.\u003c\/p\u003e\n\u003col start=\"4\"\u003e\n\u003cli\u003eCLINICAL DATA\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e4.1. Therapeutic Indications\u003c\/p\u003e\n\u003cp\u003eLocal symptomatic treatment of itching, particularly insect bites.\u003c\/p\u003e\n\u003cp\u003e4.2. Dosage and Method of Administration\u003c\/p\u003e\n\u003cp\u003eDosage\u003c\/p\u003e\n\u003cp\u003eReserved for adults and children over 2 years old.\u003c\/p\u003e\n\u003cp\u003e1 application 2 to 3 times a day.\u003c\/p\u003e\n\u003cp\u003eDo not exceed 5 days of treatment without medical advice.\u003c\/p\u003e\n\u003cp\u003ePediatric Population\u003c\/p\u003e\n\u003cp\u003eThe safety and effectiveness of APAISYLGEL 0.75%, gel for topical application in children under 2 years old have not been established.\u003c\/p\u003e\n\u003cp\u003eNo data is available.\u003c\/p\u003e\n\u003cp\u003eMethod of Administration\u003c\/p\u003e\n\u003cp\u003eCutaneous route\u003c\/p\u003e\n\u003cp\u003eApply only to the insect bite without spreading on healthy skin.\u003c\/p\u003e\n\u003cp\u003eWash hands after use.\u003c\/p\u003e\n\u003cp\u003e4.3. Contraindications\u003c\/p\u003e\n\u003cp\u003e· Hypersensitivity to the active substance or to any of the excipients listed in section 6.1\u003c\/p\u003e\n\u003cp\u003e· History of allergy to antihistamines,\u003c\/p\u003e\n\u003cp\u003e· Infected or irritated dermatoses\u003c\/p\u003e\n\u003cp\u003e· Oozing lesions\u003c\/p\u003e\n\u003cp\u003e· Eczema\u003c\/p\u003e\n\u003cp\u003e4.4. Special Warnings and Precautions for Use\u003c\/p\u003e\n\u003cp\u003eSpecial Warnings\u003c\/p\u003e\n\u003cp\u003e· Itching is only a symptom. In all cases, it requires the search for and treatment of its etiology.\u003c\/p\u003e\n\u003cp\u003e· Persistence or worsening of itching may be related to an allergy to one of the components of the preparation.\u003c\/p\u003e\n\u003cp\u003e· Given the presence of isothipendyl hydrochloride, there is a risk of cutaneous sensitization and photosensitization. In case of proven cutaneous sensitization to isothipendyl hydrochloride contained in the gel, cross-sensitizations could occur after administration of phenothiazines systemically.\u003c\/p\u003e\n\u003cp\u003e· Therefore, persistence or worsening of itching may be related to an allergy to isothipendyl hydrochloride or to one of the components of this medication.\u003c\/p\u003e\n\u003cp\u003e· The appearance of an allergy to isothipendyl hydrochloride may contraindicate in the future certain medications used systemically (certain local anesthetics, certain antihistamines).\u003c\/p\u003e\n\u003cp\u003e· Do not apply over a large area, under occlusive dressing or on injured skin due to the risk of passage of the active principle into the blood.\u003c\/p\u003e\n\u003cp\u003e· Do not apply to mucous membranes.\u003c\/p\u003e\n\u003cp\u003e· In the absence of data on cutaneous resorption, the risk of systemic effects cannot be excluded. It is all the more to be feared that the topical is used over a large area, under occlusive dressing, on injured skin (especially burned), a mucous membrane.\u003c\/p\u003e\n\u003cp\u003e· This medication contains sorbic acid (E200) and can cause local skin reactions (for example: contact dermatitis).\u003c\/p\u003e\n\u003cp\u003ePrecautions for Use\u003c\/p\u003e\n\u003cp\u003eGiven the photosensitizing effect of phenothiazines, it is preferable not to expose oneself to the sun or U.V.A during the treatment.\u003c\/p\u003e\n\u003cp\u003eIt is recommended to protect the areas treated by wearing a garment for the entire duration of the treatment to avoid any risk of photosensitization.\u003c\/p\u003e\n\u003cp\u003eThis medication is not a sunscreen.\u003c\/p\u003e\n\u003cp\u003eDo not apply to large areas of the body.\u003c\/p\u003e\n\u003cp\u003eThis medication should not be used as a care cream on healthy skin.\u003c\/p\u003e\n\u003cp\u003e4.5. Interactions with other medications and other forms of interaction\u003c\/p\u003e\n\u003cp\u003eAt recommended doses, isothipendyl hydrochloride for topical use is not likely to cause \u003c\/p\u003e\n\u003cp\u003esignificant drug interactions from a medical standpoint.\u003c\/p\u003e\n\u003cp\u003e4.6. Fertility, Pregnancy and Lactation\u003c\/p\u003e\n\u003cp\u003eTo be used with caution in pregnant or breastfeeding women due to the anticholinergic properties of isothipendyl hydrochloride. Do not apply to the breasts during breastfeeding.\u003c\/p\u003e\n\u003cp\u003e4.7. Effects on the ability to drive vehicles and use machines\u003c\/p\u003e\n\u003cp\u003eNot applicable.\u003c\/p\u003e\n\u003cp\u003e4.8. Adverse Effects\u003c\/p\u003e\n\u003cp\u003eRisk of sensitization to isothipendyl or another component. The reactions are usually cutaneous and localized at the site of application.\u003c\/p\u003e\n\u003cp\u003eVery rare cases of photosensitization have been reported.\u003c\/p\u003e\n\u003cp\u003eVery rare cases of generalized hypersensitivity reactions have been reported.\u003c\/p\u003e\n\u003cp\u003eDeclaration of Suspected Adverse Effects\u003c\/p\u003e\n\u003cp\u003eThe declaration of suspected adverse effects after authorization of the medication is important. It allows continuous monitoring of the benefit\/risk ratio of the medication. Healthcare professionals report any suspected adverse effect via the national reporting system: National Agency for the Safety of Medicines and Health Products (ANSM) and network of Regional Pharmacovigilance Centers - Website: \u003ca href=\"http:\/\/www.signalement-sante.gouv.fr\/\"\u003ewww.signalement-sante.gouv.fr\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e4.9. Overdose\u003c\/p\u003e\n\u003cp\u003eSigns of an overdose in phenothiazines: seizures (especially in infants and children), consciousness disorders, coma. Symptomatic treatment will be instituted in a specialized environment.\u003c\/p\u003e\n\u003col start=\"5\"\u003e\n\u003cli\u003ePHARMACOLOGICAL PROPERTIES\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e5.1. Pharmacodynamic Properties\u003c\/p\u003e\n\u003cp\u003ePharmacotherapeutic class: ANTIPRURITICS, INCLUDING ANTIHISTAMINES, ANESTHETICS, Topical Antihistamine.\u003c\/p\u003e\n\u003cp\u003eATC code: D04AA22.\u003c\/p\u003e\n\u003cp\u003eIsothipendyl hydrochloride from the class of aliphatic side chain phenothiazines, is a H1 antihistamine neuroleptic, anticholinergic, adrenolytic, antidopaminergic.\u003c\/p\u003e\n\u003cp\u003eAntihistamines share the property of opposing, by more or less reversible competitive antagonism, the effects of histamine notably on the skin, vessels and conjunctival, nasal, bronchial and intestinal mucous membranes.\u003c\/p\u003e\n\u003cp\u003e5.2. Pharmacokinetic Properties\u003c\/p\u003e\n\u003cp\u003eThere are no pharmacokinetic data on the use of isothipendyl hydrochloride topically.\u003c\/p\u003e\n\u003cp\u003eIsothipendyl hydrochloride belongs to the class of phenothiazines, whose maximum plasma concentration after oral absorption is reached in approximately 1 hour. After a significant first-pass hepatic effect, excretion is primarily urinary.\u003c\/p\u003e\n\u003cp\u003eBy analogy with nearby structure phenothiazines and similar pharmacological behavior, a systemic absorption of isothipendyl hydrochloride can occur from its topical application on the treated area.\u003c\/p\u003e\n\u003cp\u003e5.3. Preclinical Safety Data\u003c\/p\u003e\n\u003cp\u003eNo specific preclinical study exists for this route of administration.\u003c\/p\u003e\n\u003col start=\"6\"\u003e\n\u003cli\u003ePHARMACEUTICAL DATA\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e6.1. List of Excipients\u003c\/p\u003e\n\u003cp\u003eEdetic Acid, Sorbic Acid, non-crystallizable 70% Sorbitol, Sodium Carboxymethylcellulose, Sodium Hydroxide, purified water.\u003c\/p\u003e\n\u003cp\u003e6.2. Incompatibilities\u003c\/p\u003e\n\u003cp\u003eNot applicable.\u003c\/p\u003e\n\u003cp\u003e6.3. Shelf Life\u003c\/p\u003e\n\u003cp\u003e3 years.\u003c\/p\u003e\n\u003cp\u003e6.4. Special Precautions for Storage\u003c\/p\u003e\n\u003cp\u003eStore at a temperature not exceeding 25°C.\u003c\/p\u003e\n\u003cp\u003e6.5. Nature and Content of the Outer Packaging\u003c\/p\u003e\n\u003cp\u003eAluminum tube sealed with 30 g, internally coated with an epoxyphenolic varnish. Tube of 20, 30 or 40 g.\u003c\/p\u003e\n\u003cp\u003e6.6. Special Precautions for Disposal and Other Handling\u003c\/p\u003e\n\u003cp\u003eNo special requirements. Any unused medication or waste should be disposed of in accordance with current regulations.\u003c\/p\u003e\n\u003col start=\"7\"\u003e\n\u003cli\u003eHOLDER OF THE MARKETING AUTHORIZATION\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eP\u0026amp;G HEALTH France\u003c\/p\u003e\n\u003cp\u003e163\/165, quai aulagnier\u003c\/p\u003e\n\u003cp\u003e92600 asnieres-sur-seine\u003c\/p\u003e\n\u003col start=\"8\"\u003e\n\u003cli\u003eNUMBER(S) OF THE MARKETING AUTHORIZATION\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e· 34009 317 177 1 3 : 20 g in tube (varnished aluminum).\u003c\/p\u003e\n\u003cp\u003e· 34009 317 178 8 1 : 30 g in tube (varnished aluminum).\u003c\/p\u003e\n\u003cp\u003e· 34009 327 790 8 6 : 40 g in tube (varnished aluminum).\u003c\/p\u003e\n\u003col start=\"9\"\u003e\n\u003cli\u003eDATE OF FIRST AUTHORIZATION \/ RENEWAL OF THE AUTHORIZATION\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e[to be completed later by the holder]\u003c\/p\u003e\n\u003col start=\"10\"\u003e\n\u003cli\u003eDATE OF UPDATE OF THE TEXT\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e[to be completed later by the holder]\u003c\/p\u003e\n\u003col start=\"11\"\u003e\n\u003cli\u003eDOSIMETRY\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eNot applicable.\u003c\/p\u003e\n\u003col start=\"12\"\u003e\n\u003cli\u003eINSTRUCTIONS FOR THE PREPARATION OF RADIOPHARMACEUTICALS\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eNot applicable.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e🎉 Special Promotional Offer\u003c\/strong\u003e\u003cbr\u003eEnjoy this product at a special promotional price. \u003cstrong\u003eStandard Shipping only — please allow 7–14 days for delivery.\u003c\/strong\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Pharmarcie.com","offers":[{"title":"Default Title","offer_id":47597747208364,"sku":"P3400931717881","price":59.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0604\/4047\/7868\/files\/ApaisylInsectBiteReliefPromotion.png?v=1791560478","url":"https:\/\/pharmarcie.com\/products\/apaisyl-gel-0-75-after-insect-stings-gel-30-gr-special-offer-buy-3-get-1-apaisyl-roll-on-gel-15ml-free","provider":"Pharmarcie.com","version":"1.0","type":"link"}